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Identification and selection of resistance to

Lizhen ZHU, Jianying LI, Zhongping XU, Hakim MANGHWAR, Sijia LIANG, Suli LI, Muna ALARIQI, Shuangxia JIN, Xianlong ZHANG

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 2,   Pages 236-252 doi: 10.15302/J-FASE-2018223

Abstract: Whitefly-resistance index determination showed that a leaf having a high density of hairs had resistanceLonger leaf hairs were also important for resistance.that okra shaped leaves reduced adult whitefly oviposition preference, while glabrous leaves and high hairdensity helped not only in the reduction of the adults but also decreased oviposition preference.

Keywords： Bemisia tabaci     Gossypium genotypes     gossypol     leaf hair density     leaf hair length    

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Lodging resistance and yield potential of winter wheat: effect of planting density and genotype

Yonggui XIAO,Jianjun LIU,Haosheng LI,Xinyou CAO,Xianchun XIA,Zhonghu HE

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 2,   Pages 168-178 doi: 10.15302/J-FASE-2015061

Abstract: At the higher density, the average grain yield was 2.6% higher, even though lodging score rose by asThe higher planting density increased lodging through increased leaf area index (LAI), plant height,Higher planting density could be used to select genotypes with lodging resistance in irrigated environmentsCultivars carrying high plant density tolerance and high yield potential, such as Jimai 22 and Liangxing

Keywords： common wheat     yield potential     lodging performance     pushing resistance     leaf area index    

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Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 237-249 doi: 10.1007/s11684-016-0464-9

Abstract:

Sensory hair cells in the inner ear are responsible for sound recognition.Damage to hair cells in adult mammals causes permanent hearing impairment because these cells cannotBoth signaling pathways allow resident supporting cells to regenerate hair cells in the neonatal cochleaIn this regard, Wnt and Notch signaling has gained increased research attention in hair cell regenerationcell fate determiner Atoh1 to regulate hair cell regeneration in the mammalian cochlea.

Keywords： inner ear     cochlea     hair cell     regeneration     Wnt     Notch     signaling pathways    

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Regeneration of hair cells in the mammalian vestibular system

Wenyan Li,Dan You,Yan Chen,Renjie Chai,Huawei Li

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 143-151 doi: 10.1007/s11684-016-0451-1

Abstract:

Hair cells regenerate throughout the lifetime of non-mammalian vertebrates, allowing these animalsSince Forge and Warchol discovered the limited spontaneous regeneration of vestibular hair cells afterefforts have been exerted to trace the origin of the limited vestibular regeneration in mammals after hairFurthermore, this review highlights the current limitations of hair cell regeneration and provides thepossible solutions to regenerate functional hair cells and to partially restore vestibular function.

Keywords： utricle     hair cell     regeneration     Atoh1     Notch     Wnt    

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MicroRNA-148b promotes proliferation of hair follicle cells by targeting

Wanbao YANG,Qinqun LI,Bo SU,Mei YU

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 72-80 doi: 10.15302/J-FASE-2016089

Abstract: Previous studies have indicated that miRNAs are important for hair follicle development and growth.significantly upregulated in sheep wool follicle bulbs in anagen phase compared with the telogen phase of the haircould activate the Wnt/β-catenin signal pathway by targeting to promote the proliferation of human hair

Keywords： miR-148b     hair follicle     proliferation     NFAT5     Wnt10b    

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Characteristics of night soil and leaf co-composting using aerobic static method

Xiaojie SUN, Dunqiu WANG, Wenjing LU, Hongtao WANG

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 3,   Pages 421-427 doi: 10.1007/s11783-011-0380-9

Abstract: The main purpose of this work is to investigate the characteristics of night soil and leaf co-compostingThree influencing factors, including proportion of night soil and leaf, aeration rate and aeration patternIt was found that the 3∶1 (w∶w) mixture of night soil and leaf was capable of achieving the highest composting0.14 m ·min ·m aeration rate was most beneficial to composting, and the mixture of night soil and leaf

Keywords： night soil     leaf     aerobic compost     aeration rate     aeration pattern    

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Nanovaccines for remodeling the suppressive tumor microenvironment: New horizons in cancer immunotherapy

Kai Shi, Matthew Haynes, Leaf Huang

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4,   Pages 676-684 doi: 10.1007/s11705-017-1640-4

Abstract: Despite limited successes in clinical development, therapeutic cancer vaccines have experienced resurgence in recent years due to an enhanced emphasis upon co-mitigating factors underlying immune response. Specifically, reversing the immune-suppressive effects of the tumor microenvironment, mediated by a variety of cellular and molecular signaling mechanisms, has become fundamental toward enhancing therapeutic efficacy. Therein, our lab has implemented various nano-vaccines based on the lipid-coated calcium phosphate platform for combined immunotherapy, in which antigenic, epitope-associated peptides as well as immune-suppression inhibitors can be co-delivered, often functioning through the same formulation. In probing the mechanism of action of such systems and , an improved effect synergy can be elucidated, inspiring future preclinical efforts and hope for clinical success.

Keywords： vaccine     nanoparticle     tumor     immunotherapy     microenvironment    

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Behavioral methods for the functional assessment of hair cells in zebrafish

Qin Yang, Peng Sun, Shi Chen, Hongzhe Li, Fangyi Chen

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 178-190 doi: 10.1007/s11684-017-0507-x

Abstract:

Zebrafish is an emerging animal model for studies on auditory system. This model presents high comparability with humans, good accessibility to the hearing organ, and high throughput capacity. To better utilize this animal model, methodologies need to be used to quantify the hearing function of the zebrafish. Zebrafish displays a series of innate and robust behavior related to its auditory function. Here, we reviewed the advantage of using zebrafish in auditory research and then introduced three behavioral tests, as follows: the startle response, the vestibular-ocular reflex, and rheotaxis. These tests are discussed in terms of their physiological characteristics, up-to-date technical development, and apparatus description. Test limitation and areas to improve are also introduced. Finally, we revealed the feasibility of these applications in zebrafish behavioral assessment and their potential in the high-throughput screening on hearing-related genes and drugs.

Keywords： zebrafish (Danio rerio)     behavior     auditory     startle response     vestibular-ocular reflex     rheotaxis    

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Relationship between selenium concentration in child hair and the distribution of Kashin-Beck Disease

LI Shunjiang, YANG Linsheng, WANG Wuyi, LI Yonghua, LI Hairong, XIRAO Ruodeng

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 223-225 doi: 10.1007/s11684-007-0043-1

Abstract: focus of this study is to determine the relationship between selenium (Se) concentrations in child hairThe hair of children in typical KBD-affected areas and non-disease areas was collected, and its Se concentrationsThe Se concentrations in child hair were (0.13±0.04) and (0.18±0.07) µg/g respectively in KBD areas andIn areas supplemented with Se in Tibet, the Se concentration of hair in KBD- affected areas was higherThere is a close relationship between the Se concentrations in hair and KBD distribution.

Keywords： different     relationship     non-disease     selenium     KBD distribution    

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Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 637-650 doi: 10.1007/s11684-021-0864-3

Abstract: anticancer, anti-inflammatory, and antioxidant activities, on neomycin-induced ototoxicity in cochlear hairResults showed that apigenin significantly ameliorated the loss of hair cells and the accumulation ofabolished the effects of apigenin on the alleviation of oxidative stress and subsequent apoptosis of hairThis study provided evidence of the protective effect of apigenin on cochlear hair cells and its underlying

Keywords： apigenin     aminoglycosides     ototoxicity     oxidative stress     Nrf2 signaling pathway    

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Seasonal variations in leaf capturing of particulate matter, surface wettability and micromorphology

Huixia WANG, Hui SHI, Yangyang LI, Ya YU, Jun ZHANG

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 4,   Pages 579-588 doi: 10.1007/s11783-013-0524-1

Abstract: The seasonal changes in leaf particulate matter (PM) accumulation, surface wettability and micromorphologyDuring the study, the leaf PM retention amount of , a species with ridged leaf surfaces, was significantlyhigher than that of and , species with waxy leaf surfaces.The contact angles of water droplets on leaves decreased with leaf age except on the abaxial surfaceA significant and negative relationship existed between leaf PM retention amounts and contact angles

Keywords： contact angle     particulate matter     retention amount    

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Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice

Yuqin Men,Aizhen Zhang,Liwen Zhang,Yecheng Jin,Zhishuo Wang,Jing Zhao,Xiaolin Yu,Jian Zhang,Jiangang Gao

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 481-489 doi: 10.1007/s11684-016-0494-3

Abstract:  CKO mice) were generated using Pax2-Cre mice to investigate the function of LKB1 in inner ear hairstereociliary bundles and the migration of kinocilia are critical indicators of planar cell polarity (PCP) of hairLKB1 deficiency in LKB1Pax2 CKO mice thus disrupted hair cell planar polarity duringOur results suggest that LKB1 is required in PCP formation in cochlear hair cells in mice.

Keywords： LKB1     stereociliary bundles     kinocilium     planar cell polarity     hearing     mice    

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Alternate partial root-zone irrigation with high irrigation frequency improves root growth and reduces unproductive water loss by apple trees in arid north-west China

Shaoqing DU, Ling TONG, Shaozhong KANG, Fusheng LI, Taisheng DU, Sien LI, Risheng DING

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 2,   Pages 188-196 doi: 10.15302/J-FASE-2017176

Abstract: Root length density, stomatal conductance, photosynthetic rate, transpiration rate, leaf water use efficiency, midday stem and leaf water potentials were measured.comparison with conventional irrigation, APRI with high frequency significantly increased root length densityA significantly positive relationship between stomatal conductance and root length density was found

Keywords： alternate partial root-zone irrigation     apple tree     leaf water use efficiency     root length density     stomatal    

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Effect of current density on groundwater arsenite removal performance using air cathode electrocoagulation

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1399-1

Abstract:

• With the same charge, current density had little effect on As(III)

Keywords： Electrocoagulation     Air cathode     Arsenic     Current density     Energy consumption    

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Effects of exercise therapy on bone mineral density in early postmenopausal women: a controlled trial

Shilin DENG MD ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 323-329 doi: 10.1007/s11684-009-0061-2

Abstract: effect of a well-designed combined aerobic, resistance, and extension exercise program on bone mineral density

Keywords： early postmenopausal women     bone mineral density     exercise     effects    

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Title Author Date Type Operation

Identification and selection of resistance to

Lizhen ZHU, Jianying LI, Zhongping XU, Hakim MANGHWAR, Sijia LIANG, Suli LI, Muna ALARIQI, Shuangxia JIN, Xianlong ZHANG

Journal Article

Lodging resistance and yield potential of winter wheat: effect of planting density and genotype

Yonggui XIAO,Jianjun LIU,Haosheng LI,Xinyou CAO,Xianchun XIA,Zhonghu HE

Journal Article

Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Journal Article

Regeneration of hair cells in the mammalian vestibular system

Wenyan Li,Dan You,Yan Chen,Renjie Chai,Huawei Li

Journal Article

MicroRNA-148b promotes proliferation of hair follicle cells by targeting

Wanbao YANG,Qinqun LI,Bo SU,Mei YU

Journal Article

Characteristics of night soil and leaf co-composting using aerobic static method

Xiaojie SUN, Dunqiu WANG, Wenjing LU, Hongtao WANG

Journal Article

Nanovaccines for remodeling the suppressive tumor microenvironment: New horizons in cancer immunotherapy

Kai Shi, Matthew Haynes, Leaf Huang

Journal Article

Behavioral methods for the functional assessment of hair cells in zebrafish

Qin Yang, Peng Sun, Shi Chen, Hongzhe Li, Fangyi Chen

Journal Article

Relationship between selenium concentration in child hair and the distribution of Kashin-Beck Disease

LI Shunjiang, YANG Linsheng, WANG Wuyi, LI Yonghua, LI Hairong, XIRAO Ruodeng

Journal Article

Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair

Journal Article

Seasonal variations in leaf capturing of particulate matter, surface wettability and micromorphology

Huixia WANG, Hui SHI, Yangyang LI, Ya YU, Jun ZHANG

Journal Article

Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice

Yuqin Men,Aizhen Zhang,Liwen Zhang,Yecheng Jin,Zhishuo Wang,Jing Zhao,Xiaolin Yu,Jian Zhang,Jiangang Gao

Journal Article

Alternate partial root-zone irrigation with high irrigation frequency improves root growth and reduces unproductive water loss by apple trees in arid north-west China

Shaoqing DU, Ling TONG, Shaozhong KANG, Fusheng LI, Taisheng DU, Sien LI, Risheng DING

Journal Article

Effect of current density on groundwater arsenite removal performance using air cathode electrocoagulation

Journal Article

Effects of exercise therapy on bone mineral density in early postmenopausal women: a controlled trial

Shilin DENG MD ,

Journal Article